nephrotic syndrome

noun

: an abnormal condition that is marked by deficiency of albumin in the blood and its excretion in the urine due to altered permeability of the glomerular basement membranes

Examples of nephrotic syndrome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This rare condition is most often seen in adults with nephrotic syndrome, a type of kidney disease in which excess protein leaks into the urine. Alicen Nelson Md, Verywell Health, 27 Mar. 2025 Since Harper's diagnosis, Becca has found solace in social media, sharing Harper’s journey with nephrotic syndrome on TikTok in hopes of connecting with other parents whose children had been diagnosed with the condition. Jordan Greene, People.com, 19 Mar. 2025 Ameera did indeed have a kidney disease, explaining her nephrotic syndrome symptoms. Amitha Kalaichandran, Discover Magazine, 15 Apr. 2019

Word History

First Known Use

1931, in the meaning defined above

Time Traveler
The first known use of nephrotic syndrome was in 1931

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Cite this Entry

“Nephrotic syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nephrotic%20syndrome. Accessed 5 Sep. 2025.

Medical Definition

nephrotic syndrome

noun
: an abnormal condition that is marked especially by a deficiency of albumin in the blood and excess excretion of protein in the urine due to altered permeability of the glomerular basement membranes (as from membranous glomerulonephritis, minimal change disease, or diabetes mellitus)

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